A groundbreaking new blood test for Alzheimer’s disease could revolutionize your ability to plan ahead.  The new test measures the level of a protein called “p-tau 217” and a biomarker known as the “amyloid 42/40 ratio” (which measures two types of amyloid proteins) both found in blood.. The p-tau 217 protein is a key marker in the diagnosis of mild cognitive impairment and early-stage Alzheimer’s disease, and its presence can indicate the onset of cognitive decline well before symptoms become noticeable.  Indeed, the recent studies have shown this new test to have a remarkable 90% accuracy rate in determining whether memory loss is due to Alzheimer’s disease, even in its early stages

The Science Behind the Test

Traditional methods for diagnosing Alzheimer’s, such as brain imaging and spinal taps, are invasive, costly, and often only used when symptoms are already advanced. In contrast, this new blood test offers a less invasive and more accessible option, potentially allowing for widespread screening and earlier detection.

Recent studies using the new blood test have demonstrated the effectiveness of the p-tau 217 test in distinguishing Alzheimer’s from other forms of dementia, as well as from normal age-related cognitive decline. One such study, published in the journal JAMA Neurology, followed 1,213 people with an average age of 74 who were undergoing cognitive evaluations in both primary care and specialty clinics in Sweden. Each person’s blood was tested using p-tau217, and the results were combined with blood measures of beta-amyloid 40/42 to develop a final score. In clinical trials, the test has shown high sensitivity and specificity, meaning it can accurately identify those with Alzheimer’s and reduce the risk of false positives.

Legal Opportunities of Early Detection

At Widlast Legal, we recognize that diagnosis of Alzheimer’s or other cognitive decline brings with it not just medical challenges, but also critical legal considerations. It’s essential to address these issues promptly to safeguard the rights and interests of those affected. Here are some key legal areas that should be reviewed upon an early detection or diagnosis:

1. Financial Powers of Attorney: Individuals who still have sufficient cognitive capacity can make informed decisions about who will manage their finances and healthcare decisions when they are no longer able to do so. Establishing or updating Powers of Attorney is crucial in ensuring that the designated person reflects the individual’s wishes.
2. Wills and Trusts: Early detection provides an opportunity to review and update estate plans. This includes revisiting wills, trusts, and beneficiary designations to ensure that they align with the individual’s current intentions. Given the progressive nature of Alzheimer’s, timely updates are essential to avoid potential disputes later on.
3. Advance Health Care Directives: At Widlast Legal, we prepare these  documents to express the individual’s wishes regarding medical treatment, personal care and end-of-life care.  For someone with an early diagnosis, it is especially important that this document include your views about personal care since you may live many years needing help with your personal activities of daily living (dressing, bathing, feeding, etc) which are not considered medical care, and thus not covered in the forms provided by many physician offices.  An early diagnosis allows for thoughtful consideration and documentation of these preferences while the individual is still fully capable of making such decisions, and.
4. Asset Protection: Alzheimer’s and other forms of cognitive decline can lead to significant long-term care needs, which can deplete an individual’s financial resources. Early planning can help protect assets, ensuring that the person’s needs are met without exhausting their estate.

The introduction of this new Alzheimer’s test represents a breakthrough in medical science, offering hope for earlier intervention and improved quality of life. However, it also underscores the importance of timely legal planning. By addressing these issues early, families can ensure that their loved ones are protected and that their wishes are honored. At Widlast Legal, we are here to help you navigate these challenges with expertise and care.